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The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis

机译：NaD依赖性脱乙酰酶sirtuin-1调节骨关节炎中软骨细胞中成骨转录激活因子Runt相关转录因子2（Runx2）的表达和基质金属蛋白酶（mmp）-13的产生

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Koh Terauchi; Hajime Kobayashi; Kanaka Yatabe; Naoko Yui; Hiroto Fujiya; Hisateru Niki; Haruki Musha; Kazuo Yudoh;
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1. The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis [J] . Koh Terauchi, Hajime Kobayashi, Kanaka Yatabe, International Journal of Molecular Sciences . 2016,第7期

机译：NAD依赖的脱乙酰基酶Sirtuin-1调节骨关节炎软骨细胞中成骨转录激活因子矮子相关转录因子2（Runx2）的表达和基质金属蛋白酶（MMP）-13的产生。
2. NAD-DEPENDENT DEACETYLASE SIRTUIN-1 MEDIATES THE MECHANICAL STRESS-INDUCED DEGENERATION OF ARTICULAR CARTILAGE IN OSTEOARTHRITIS: MECHANICAL STRESS STIMULATES THE EXPRESSION OF OSTEOGENIC TRANSCRIPTION FACTOR RUNX2 VIA THE SRITUIN-1 ACTIVATION IN CHONDROCYTES [J] . Osteoarthritis and cartilage . 2020,第Suppla1期

机译：NAD依赖性脱乙酰酶Sirtuin-1介导骨关节炎的机械应力诱导的关节软骨退化：机械应力刺激通过软骨细胞中的Srituin-1活化刺激成骨转录因子Runx2的表达
3. Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification [J] . Riko Nishimura, Makoto Wakabayashi, Kenji Hata, The Journal of biological chemistry . 2012,第40期

机译：Ostorix通过基质金属蛋白酶13（MMP13）表达与转录因子Runx2相关联的基质金属蛋白酶13（MMP13）表达来调节软骨蛋白基质的钙化和降解
4. Interleukin-4 Regulates the Expression of Thymus-and Activation-Regulated Chemokine (TARC)/CCL17 by a Signal Transducer and Activator of Transcription 6 (STAT6)-Dependent Mechanism [C] . J. Horejs-Hoeck, G. Wirnsberger, D. Hebenstreit, Collegium Internationale Allergologicum . 2007

机译：白细胞介素-4调节胸腺和活化调节的趋化因子（TARC）/ CCL17的表达通过转录6（STAT6） - 依赖机构的信号传感器和活化剂
5. Matrix Metalloproteinase genes are transcriptionally regulated by E2F transcription factors: A link between cell cycle control and metastatic progression. [D] . Johnson, Jacqueline L. 2012

机译：基质金属蛋白酶基因受E2F转录因子的转录调控：细胞周期控制与转移进程之间的联系。
6. The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis [O] . Koh Terauchi, Hajime Kobayashi, Kanaka Yatabe, 2016

机译：NAD依赖的脱乙酰基酶Sirtuin-1调节骨关节炎软骨细胞中成骨转录激活因子矮子相关转录因子2（Runx2）的表达和基质金属蛋白酶（MMP）-13的产生。
7. NAD-dependent deacetylase sirtuin-1 mediates the mechanical stress-induced degeneration of articular cartilage in osteoarthritis: mechanical stress stimulates the expression of osteogenic transcription factor RUNX2 via the srituin-1 activation in chondrocytes [O] . K. Yudoh, N. Yui, T. Kumai, 2020

机译：NAD依赖性的脱乙酰酶Sirtuin-1介导骨关节炎的机械应力诱导的关节软骨变性：机械应力刺激软骨细胞中Srituin-1活化的骨质发生转录因子Runx2的表达

The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis

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